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1

The effect of hydrazide linkers on hyaluronan hydrazone hydrogels

Šedová, Petra, Buffa, Radovan, Šilhár, Peter, Kovářová, Lenka, Vágnerová, Hana, Bednařík, Jiří, Basarabová, Ivana, Hejlová, Lenka, Ščigalková, Ivana, Šimek, Matěj, Velebný, Vladimír

Journal:

Carbohydrate Polymers

Year:

2019

Language:

english

File:

PDF, 698 KB

english, 2019

2

Facile and Efficient Synthesis of 6-(Hydroxymethyl)purines.

Peter Silhar, Radek Pohl, Ivan Votruba, Michal Hocek

Journal:

Year:

2005

File:

PDF, 229 KB

2005

3

Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides

Peter Šilhár, Michal Hocek, Radek Pohl, Ivan Votruba, I-hung Shih, Eric Mabery, Richard Mackman

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 678 KB

english, 2008

4

Parallel synthesis and nucleic acid binding properties of C(6′)-α-functionalized bicyclo-DNA

Peter Šilhár, Christian J. Leumann

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 520 KB

english, 2010

5

Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: Synthesis and evaluation of 6-substituted purine l-ribonucleosides

Michal Hocek, Peter Šilhár, I-hung Shih, Eric Mabery, Richard Mackman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 125 KB

english, 2006

6

Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease

Peter Šilhár, Sami Alakurtti, Kateřina Čapková, Feng Xiaochuan, Charles B. Shoemaker, Jari Yli-Kauhaluoma, Kim D. Janda

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 2.07 MB

english, 2011

7

Synthesis of (purin-6-yl)acetates and 6-(2-hydroxyethyl)purines via cross-couplings of 6-chloropurines with the Reformatsky reagent

Zbyněk Hasník, Peter Šilhár, Michal Hocek

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 133 KB

english, 2007

8

Synthesis of 2-Substituted 6-(Hydroxymethyl)purine Bases and Nucleosides

Šilhár, Peter, Pohl, Radek, Votruba, Ivan, Hocek, Michal

Journal:

Collection of Czechoslovak Chemical Communications

Year:

2005

Language:

english

File:

PDF, 221 KB

english, 2005

9

The first synthesis and cytostatic activity of novel 6-(fluoromethyl)purine bases and nucleosides

Šilhár, Peter, Pohl, Radek, Votruba, Ivan, Hocek, Michal

Journal:

Organic & Biomolecular Chemistry

Year:

2005

Language:

english

File:

PDF, 207 KB

english, 2005

10

Facile and Efficient Synthesis of 6-(Hydroxymethyl)purines

Šilhár, Peter, Pohl, Radek, Votruba, Ivan, Hocek, Michal

Journal:

Organic Letters

Year:

2004

Language:

english

File:

PDF, 56 KB

english, 2004

11

Evaluation of adamantane hydroxamates as botulinum neurotoxin inhibitors: Synthesis, crystallography, modeling, kinetic and cellular based studies

Šilhár, Peter, Silvaggi, Nicholas R., Pellett, Sabine, Čapková, Kateřina, Johnson, Eric A., Allen, Karen N., Janda, Kim D.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 828 KB

english, 2013

12

Targeting Botulinum A Cellular Toxicity: A Prodrug Approach

Šilhár, Peter, Eubanks, Lisa M., Seki, Hajime, Pellett, Sabine, Javor, Sacha, Tepp, William H., Johnson, Eric A., Janda, Kim D.

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 4.09 MB

english, 2013

13

Synthesis/biological evaluation of hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain

Seki, Hajime, Pellett, Sabine, Šilhár, Peter, Stowe, G. Neil, Blanco, Beatriz, Lardy, Matthew A., Johnson, Eric A., Janda, Kim D.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 926 KB

english, 2014

14

C-Terminus of Botulinum A Protease Has Profound and Unanticipated Kinetic Consequences upon the Catalytic Cleft

Šilhár, Peter, Lardy, Matthew A., Hixon, Mark S., Shoemaker, Charles B., Barbieri, Joseph T., Struss, Anjali K., Lively, Jenny M., Javor, Sacha, Janda, Kim D.

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.44 MB

english, 2013

15

Antioxidative properties of Sambacus nigra extracts

Topoľská, Dominika, Valachová, Katarína, Rapta, Peter, Šilhár, Stanislav, Panghyová, Elena, Horváth, Anton, Šoltés, Ladislav

Journal:

Chemical Papers

Year:

2015

Language:

english

File:

PDF, 358 KB

english, 2015

16

Hydroxymethylations of Aryl Halides by Pd-Catalyzed Cross-Couplings with (Benzoyloxy)methylzinc Iodide - Scope and Limitations of the Reaction

Hasník, Zbyněk, Šilhár, Peter, Hocek, Michal

Journal:

Year:

2008

Language:

english

File:

PDF, 80 KB

english, 2008

17

Synthesis and Cytostatic Activity of Novel 6-(Difluoromethyl)purine Bases and Nucleosides

Šilhár, Peter, Pohl, Radek, Votruba, Ivan, Hocek, Michal

Journal:

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

18

Synthesis of the Sugar Building Block of Bicyclo-RNA

Haziri, Arben, Silhar, Peter, Renneberg, Dorte, Leumann, Christian

Journal:

Year:

2010

Language:

english

File:

PDF, 110 KB

english, 2010

19

Cytostatic and Antiviral 6-Arylpurine Ribonucleosides VIII. Synthesis and Evaluation of 6-Substituted Purine 3'-Deoxyribonucleosides

Hocek, Michal, Šilhár, Peter, Pohl, Radek

Journal:

Collection of Czechoslovak Chemical Communications

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

20

Cellular Protection of SNAP-25 against Botulinum Neurotoxin/A: Inhibition of Thioredoxin Reductase through a Suicide Substrate Mechanism

Seki, Hajime, Xue, Song, Pellett, Sabine, Šilhár, Peter, Johnson, Eric A., Janda, Kim D.

Journal:

Journal of the American Chemical Society

Year:

2016

Language:

english

File:

PDF, 1.33 MB

english, 2016

21

Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl-2-(hydroxymethyl)purine Bases and Nucleosides

Šilhár, Peter, Pohl, Radek, Votruba, Ivan, Klepetářová, Blanka, Hocek, Michal

Journal:

Collection of Czechoslovak Chemical Communications

Year:

2006

Language:

english

File:

PDF, 221 KB

english, 2006

22

Examination of α-exosite inhibitors against Botulinum neurotoxin A protease through structure-activity relationship studies of chicoric acid

Xue, Song, Seki, Hajime, Remes, Marek, Šilhár, Peter, Janda, Kim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 1.68 MB

english, 2017